Experimental Nonclinical Pharmacokineticist

Inactive

Reference Number: 895664-W
Type of placement: Permanent, Permanent
Location: Switzerland

Introduction:

Our client is a leading biopharmaceutical company specialized in the discovery and development of small molecules, to transform the horizon of therapeutic options. They have a broad portfolio of innovative drugs in the pipeline, an experienced team, a fully-functional research center, and a strong balance sheet – the ideal constellation to bringing R&D efforts to business success. For their Nonclinical Pharmacokinetics and Metabolism Department (DMPK) we are seeking an Experimental Nonclinical Pharmacokineticist.

Main Responsibilities:

  • Heading the department's animal research laboratory
  • Planning, conducting, monitoring and reporting of all internal and external animal studies required for the support of multiple drug discovery and nonclinical development programs
  • Introducing new in vivo techniques enabling mechanistic studies
  • Acting as the DMPK representative in multidisciplinary discovery and development project teams Responsible for the co-ordination of all DMPK activities from early lead optimization up to regulatory filing
  • Responsible for the preparation of regulatory and non-regulatory documents, i.e. IB, IND, NDA, study reports, scientific publications

Qualifications and Experience:

  • PhD in a scientific area related to pharmacokinetics
  • At least 3 to 5 years of industry experience in preclinical pharmacokinetics covering drug discovery and development
  • Demonstrated experience in pharmacokinetic animal models
  • Proficient in the use of pharmacokinetic software packages, e.g. Phoenix WinNonlin
  • Familiar with EMA/FDA/ICH guidelines
  • Basic background in drug metabolism
  • Publication record
  • Very good team-working and communication skills with the capability to work in a dynamic and interdisciplinary environment
  • Excellent command of English; German or any other major European language would be an asset
  • Relevant working/residency permit or Swiss/EU-Citizenship required