SENIOR DATA SCIENTIST R PROGRAMMER – 5967 URA

 

Our client, an innovative and dynamic bio-pharmaceutical company headquartered in Switzerland, covering multiple therapeutic areas, committed into delivering products on the market over the next 5 years, is looking a SENIOR DATA SCIENTIST R PROGRAMMER for a 12 months contract ( extendable) based in Basel.

 

Main Responsibilities:

 

  • Support statistics, programming and data management groups across Biometry to explore, review, understand and explain clinical data.
  • Oversee the creation of customized applications to allow dynamic exploration of clinical trial data and results at critical study milestones (especially following major database locks).
  • Use and promote reproducible research methods to ensure reports may be refreshed efficiently as data is updated.
  • Communicate results and educate others through insightful visualizations, reports, publications and presentations.
  • Create outputs that may be used for publication, regulatory submissions, internal decision-making, market tracking, or other uses.
  • Support statisticians with ad-hoc exploratory analyses following key database locks.
  • Champion new ways of working with and presenting clinical data and develop educational material to lead the adoption of these methods across Biometry.
  • Support data-monitoring initiatives including risk-based monitoring by preparing & sharing outputs /reports to Clinical Trial Teams.
  • Utilize a diverse array of data mining, analytics and modeling techniques to generate and test working hypotheses, deliver insights and support actionable recommendations to Clinical Teams.
  • Proactively search for trends in clinical data of ongoing studies, including deviations from assumptions.
  • Lead development of in-house R packages.
  • Monitor trends in usage of new technologies across the industry with a critical eye.
  • Contribute/review new standards, policies, templates and procedures.
  • Ensure processes are followed as defined in quality documents.
  • Ensure standards for documents, metadata and data are created, maintained and applied.

 Qualifications and Experience:

 

  • Relevant Swiss working/residency permit and/or Swiss/EU-Citizenship required;
  • Master’s degree in the field of computer science, machine learning, applied statistics, mathematics, with at least 5 years of relevant programming experience, of which at least 3 within a pharmaceutical company or a clinical research organization (CRO).
  • Experience extracting, cleaning, preparing, modeling and visualizing data; advanced knowledge of one or more statistical programming languages such as R, SAS, Python, Julia; advanced knowledge of R packages such as dplyr for data manipulation and ggplot2 for plotting.
  • Familiar with generation of interactive reports/dashboards, e.g., R, Shiny, Dash, Spotfire, Tableau, QlikSense.
  • Extensive experience with creating reproducible reports through code versioning using RMarkdown or Notebooks.
  • Excellent knowledge of processes related to statistical analyses in clinical trials.
  • Knowledge and understanding of CDISC, especially SDTM and ADaM.
  • Strong analytical skills, attention to detail, ability to manage/prioritize multiple projects.
  • Entrepreneurial mindset and self-direction, ability to spot trends, teach others and willingness to learn new techniques.
  • Must be able to work according to operating procedures, specifications and timelines.
  • Knowledge of international clinical research regulations and requirements (ICH-GCP) and 21 CFR Part 11.
  • Excellent presentation, interpersonal skills, and a positive communication style.